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Giovanni Luca Gravina Selected Research

3,3,3- trifluoro- 2- (4- isobutylphenyl)propanoic acid

1/2014Trifluoroibuprofen inhibits α-methylacyl coenzyme A racemase (AMACR/P504S), reduces cancer cell proliferation and inhibits in vivo tumor growth in aggressive prostate cancer models.

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Giovanni Luca Gravina Research Topics

Disease

61Neoplasms (Cancer)
10/2023 - 07/2004
52Prostatic Neoplasms (Prostate Cancer)
10/2023 - 03/2003
20Glioblastoma (Glioblastoma Multiforme)
01/2022 - 06/2014
13Neoplasm Metastasis (Metastasis)
04/2023 - 05/2004
8Carcinoma (Carcinomatosis)
12/2014 - 09/2002
7Glioma (Gliomas)
01/2022 - 12/2014
7Rhabdomyosarcoma
01/2022 - 01/2011
4Pain (Aches)
02/2022 - 01/2015
4Embryonal Rhabdomyosarcoma
01/2022 - 01/2011
3Brain Neoplasms (Brain Tumor)
01/2022 - 05/2018
3Prostatic Hyperplasia (Benign Prostatic Hyperplasia)
03/2013 - 04/2004
2Sarcoma (Soft Tissue Sarcoma)
01/2022 - 01/2020
2Breast Neoplasms (Breast Cancer)
12/2020 - 05/2014
2Osteolysis
12/2019 - 09/2015
2Necrosis
05/2017 - 03/2008
2Carcinogenesis
02/2017 - 01/2014
2Inflammation (Inflammations)
01/2017 - 05/2014
1Squamous Cell Carcinoma (Epidermoid Carcinoma)
12/2023
1Adenocarcinoma
10/2023
1Infertility (Sterility)
03/2021

Drug/Important Bio-Agent (IBA)

13AndrogensIBA
09/2016 - 03/2003
10bicalutamide (Casodex)FDA LinkGeneric
12/2011 - 09/2002
9Hormones (Hormone)IBA
12/2017 - 06/2009
9ErbB Receptors (EGF Receptor)IBA
10/2011 - 03/2003
7Androgen Receptors (Androgen Receptor)IBA
12/2017 - 07/2004
7DNA (Deoxyribonucleic Acid)IBA
01/2017 - 01/2011
6Docetaxel (Taxotere)FDA Link
12/2019 - 06/2009
6Tyrosine Kinase InhibitorsIBA
10/2009 - 03/2003
5EphrinsIBA
10/2023 - 10/2017
5Phosphotransferases (Kinase)IBA
01/2020 - 07/2004
5Cyclin D1IBA
12/2017 - 06/2009
5Gefitinib (Iressa)FDA Link
11/2007 - 03/2003
4Mechanistic Target of Rapamycin Complex 1IBA
01/2022 - 08/2011
4Histone Deacetylase InhibitorsIBA
10/2021 - 03/2012
4Temozolomide (Temodar)FDA LinkGeneric
01/2020 - 01/2017
4Mitogen-Activated Protein Kinase Kinases (MEKs)IBA
09/2018 - 01/2011
4Azacitidine (5 Azacytidine)FDA Link
07/2016 - 05/2008
4selinexorIBA
01/2016 - 10/2014
4Epidermal Growth Factor (EGF)IBA
11/2006 - 05/2004
3PBI-05204IBA
01/2022 - 01/2020
3thiamine triphosphorate (TTP)IBA
01/2020 - 06/2014
3Mechanistic Target of Rapamycin Complex 2IBA
10/2019 - 08/2011
3Proteins (Proteins, Gene)FDA Link
10/2019 - 05/2008
3belinostatIBA
10/2019 - 03/2012
3U 0126 (UO 126)IBA
09/2018 - 01/2011
3SurvivinIBA
01/2016 - 06/2014
3Androgen Antagonists (Antiandrogens)IBA
10/2009 - 09/2002
2Eph Family Receptors (Eph Receptors)IBA
10/2023 - 01/2020
2oleandrinIBA
01/2022 - 01/2022
2Reactive Oxygen Species (Oxygen Radicals)IBA
08/2020 - 04/2019
2CytokinesIBA
08/2020 - 03/2008
2pyrimidineIBA
05/2020 - 01/2016
2trans-sodium crocetinate (crocetin)IBA
01/2020 - 01/2014
2ErythropoietinFDA Link
01/2020 - 10/2017
2EphA1 Receptor (Eph Receptor)IBA
01/2020 - 05/2018
2Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA
01/2020 - 01/2014
2Collagen Type I (Type I Collagen)IBA
12/2019 - 09/2015
2taxaneIBA
12/2019 - 05/2014
2Therapeutic UsesIBA
10/2019 - 12/2015
2AntioxidantsIBA
04/2019 - 02/2008
2givinostat hydrochlorideIBA
01/2019 - 01/2019
2Histone Deacetylases (Histone Deacetylase)IBA
01/2019 - 01/2017
2givinostatIBA
01/2019 - 01/2019
2EnzymesIBA
02/2017 - 09/2009
2Type 5 Cyclic Nucleotide PhosphodiesterasesIBA
02/2017 - 09/2009
2Nerve Growth Factor (NGF)IBA
07/2016 - 01/2007
2Exportin 1 ProteinIBA
12/2015 - 12/2014
2KPT-251IBA
12/2015 - 10/2014
2Analgesics (Analgesic Drugs)IBA
01/2015 - 07/2005
2lysyl- arginyl- alanyl- lysyl- alanyl- lysyl- threonyl- threonyl- lysyl- lysyl- arginine (PKCS)IBA
06/2014 - 01/2011
2palomid 529IBA
06/2014 - 08/2011
2crocinIBA
01/2014 - 01/2013
2MethyltransferasesIBA
03/2013 - 12/2011
2Erlotinib Hydrochloride (CP 358,774)FDA Link
10/2011 - 10/2009
2Cisplatin (Platino)FDA LinkGeneric
08/2011 - 06/2009
2TensinsIBA
11/2009 - 08/2007
2Phosphoric Monoester Hydrolases (Phosphatases)IBA
11/2009 - 08/2007
2Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
08/2008 - 03/2008
2Finasteride (Propecia)FDA LinkGeneric
07/2008 - 04/2005
2lestaurtinibIBA
09/2007 - 01/2007
2Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
04/2005 - 05/2004
1Peptides (Polypeptides)IBA
01/2022
1Cell-Penetrating PeptidesIBA
01/2022
1Proliferating Cell Nuclear Antigen (PCNA)IBA
01/2022
1ABTL0812IBA
01/2022
1Cardiac GlycosidesIBA
01/2022
1sulforaphaneIBA
10/2021
1entinostat (MS 275)IBA
10/2021
1Cyclin AIBA
01/2021
1romidepsin (FK228)FDA Link
01/2021

Therapy/Procedure

32Radiotherapy
04/2023 - 01/2010
27Therapeutics
10/2023 - 07/2004
9Drug Therapy (Chemotherapy)
02/2020 - 09/2013
7Castration
12/2019 - 10/2009
3Cryosurgery
02/2022 - 01/2015
2Adjuvant Radiotherapy
12/2023 - 11/2016
2Aftercare (After-Treatment)
01/2017 - 01/2015
2Radiofrequency Ablation
08/2016 - 03/2016
2Prostatectomy (Retropubic Prostatectomy)
09/2007 - 09/2007
1Ablation Techniques
02/2022